Acetyl chloride → 3-Acetylamino-2-benzoyl-5-chloro-1-(ethoxycarbonyl)indole

HRID 379795Notes

Reaction equation

HRID 379795 reaction equation
[NH2:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([Cl:11])[CH:9]=2)[N:4]([C:12]([O:14][CH2:15][CH3:16])=[O:13])[C:3]=1[C:17](=[O:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.[C:25](Cl)(=[O:27])[CH3:26]>>[C:25]([NH:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([Cl:11])[CH:9]=2)[N:4]([C:12]([O:14][CH2:15][CH3:16])=[O:13])[C:3]=1[C:17](=[O:24])[C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)(=[O:27])[CH3:26]

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 183680013-Amino-2-benzoyl-5-chloro-1-(ethoxycarbonyl)indole

Product 1

HCID 183677233-Acetylamino-2-benzoyl-5-chloro-1-(ethoxycarbonyl)indole

Procedure

The title compound was prepared according to the procedure described in step 1 of Example 2 (Method A) and from 3-amino-2-benzoyl-5-chloro-1-(ethoxycarbonyl)indole (step 1) and acetyl chloride.

Sources & evidence

ORD record
ord-6dab73c0f2c84fd79456315a3198ef4f
Source dataset
uspto-grants-2001_10
Patent number
US06300363B1

Reaction notes

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