HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-[(ethoxycarbonyl)amino]benzonitrile → 3-Amino-5-bromo-6-chloro-1-(ethoxycarbonyl)-2-(6-methylpyridine-2-carbonyl)indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-[(ethoxycarbonyl)amino]benzonitrile | HCID 18367888 | — |
| Reactant | 2-Bromo-1-(6-methylpyridin-2-yl)ethanone hydrobromide | HCID 22291417 | — |
| Product | 3-Amino-5-bromo-6-chloro-1-(ethoxycarbonyl)-2-(6-methylpyridine-2-carbonyl)indole | HCID 18367735 | — |
Reaction Steps
The title compounds were prepared according to the procedure described in step 2 of Example 1 from 4-chloro-2-(ethoxycarbonylamino)benzonitrile and 2-bromoacetyl-6-methylpyridine hydrobromide (H. Erlenmeyer, J. Jenni, and B. Prijs, J. Med. Pharm. Chem., 1961, 3, 561-566).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06300363B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-1ff0e494e0754b40abad62969b9db158 |
| Source note | uspto-grants-2001_10 |