Acetyl chloride → HCID 18367746, compound

HRID 379828Notes

Reaction equation

HRID 379828 reaction equation
[NH2:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([Cl:11])=[CH:8][CH:9]=2)[NH:4][C:3]=1[C:12](=[O:22])[C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([NH2:21])=[O:20])[CH:14]=1.[C:23](Cl)(=[O:25])[CH3:24]>C(OCC)(=O)C.CCCCCC>[C:23]([NH:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([Cl:11])=[CH:8][CH:9]=2)[NH:4][C:3]=1[C:12](=[O:22])[C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([NH2:21])=[O:20])[CH:14]=1)(=[O:25])[CH3:24]

Participants

4

Reactant 2

HCID 6367Acetyl chlorideHCID 18367733HCID 18367733, compound

Product 1

HCID 18367746HCID 18367746, compound

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

The title compound was prepared according to the procedure described in Example 19 employing 3-amino-2-(3-aminocarbonylbenzoyl)-6-chloroindole (Example 128) and acetyl chloride. m.p.: 243-247° C. (ethyl acetate/hexane)

Sources & evidence

ORD record
ord-05f856309ebd49e3ad159a474e416c6e
Source dataset
uspto-grants-2001_10
Patent number
US06300363B1

Reaction notes

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