Acetyl chloride → HCID 18368143, compound

HRID 379847Notes

Reaction equation

HRID 379847 reaction equation
[NH2:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([Cl:11])=[CH:8][CH:9]=2)[NH:4][C:3]=1[C:12]([CH:14]1[CH2:19][CH2:18][CH2:17][CH:16]([CH3:20])[CH2:15]1)=[O:13].[C:21](Cl)(=[O:23])[CH3:22]>C(OCC)(=O)C.CCCCCC>[C:21]([NH:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([Cl:11])=[CH:8][CH:9]=2)[NH:4][C:3]=1[C:12]([CH:14]1[CH2:19][CH2:18][CH2:17][CH:16]([CH3:20])[CH2:15]1)=[O:13])(=[O:23])[CH3:22]

Participants

4

Reactant 2

HCID 6367Acetyl chlorideHCID 18368093HCID 18368093, compound

Product 1

HCID 18368143HCID 18368143, compound

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

The title compound was prepared according to the procedure described in Example 19 employing 3-amino-6-chloro-2-(3-methylcyclohexylcarbonyl)indole (Example 144) and acetyl chloride. m.p.: 202-203° C. (ethyl acetate/hexane)

Sources & evidence

ORD record
ord-e00bc63b49e04c96963ad60b9fdd0fc6
Source dataset
uspto-grants-2001_10
Patent number
US06300363B1

Reaction notes

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