Hydrochloric Acid → HCID 18367938, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of methyl 6-methoxy-3-nitroindole-2-carboxylate (step 1) in ethanol (10 ml) and water(5 ml) was added K2CO3 and the mixture was stirred for 4 hr at 40° C. The mixture was acidified with 2N HCl and extracted with ethyl acetate (20 ml×2). The organic layer was washed with brine (10 ml) and dried (MgSO4). Removal of solvent gave product as an oil. tlc: Rf=0.1 (50% ethyl acetate in hexanes)

Provenance & Evidence