Isovaleryl chloride → HCID 18368086, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in Ex. 19 from 3-amino-6-chloro-2-(3-furoyl)indole (Example 79) and isovaleryl chloride. m.p.: 202-203° C. (recrystallized from ethyl acetate) 1H-NMR (CDCl3) δ: 10.10 (1 H, br s), 8.28 (1 H, d, J=8.8 Hz), 8.23 (1 H, br s), 8.11 (1 H, dd, J=0.7, 1.5 Hz), 7.59 (1 H, dd, J=1.5, 1.8 Hz), 7.31 (1 H, d, J=1.8 Hz), 7.10 (1 H, dd, J=1.8, 8.8 Hz), 6.89 (1 H, dd, J=0.7, 1.8 Hz), 2.39-2.22 (3 H, m), 1.06 (6 H, d, J=6.6 Hz).

Provenance & Evidence