3-Chloropropionyl chloride → HCID 18368121, compound

HRID 379898Notes

Reaction equation

HRID 379898 reaction equation
[NH2:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([Cl:11])=[CH:8][CH:9]=2)[NH:4][C:3]=1[C:12]([C:14]1[CH:19]=[C:18]([CH3:20])[CH:17]=[CH:16][N:15]=1)=[O:13].[Cl:21][CH2:22][CH2:23][C:24](Cl)=[O:25]>>[Cl:11][C:7]1[CH:6]=[C:5]2[C:10]([C:2]([NH:1][C:24](=[O:25])[CH2:23][CH2:22][Cl:21])=[C:3]([C:12]([C:14]3[CH:19]=[C:18]([CH3:20])[CH:17]=[CH:16][N:15]=3)=[O:13])[NH:4]2)=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 693643-Chloropropionyl chlorideHCID 183680983-Amino-6-chloro-2-(4-methylpyridine-2-carbonyl)indole

Product 1

HCID 18368121HCID 18368121, compound

Procedure

The title compound was prepared according to the procedure described in Example 19 employing 3-amino-6-chloro-2-(4-methylpyridine-2-carbonyl)indole (Example 70) and 3-chloropropionyl chloride.

Sources & evidence

ORD record
ord-eaa0b90ff0c942ec88c1a6fefe2f85ee
Source dataset
uspto-grants-2001_10
Patent number
US06300363B1

Reaction notes

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