HCID 131722881, compound → (3Rs,4s)-4-(biphenyl-4-yloxy)-1-pyridin-3-yl-pentan-3-ol

Participants

Reaction Steps

Prepared according to the method described in Example 1d) from (2S, 3RS)-2-(biphenyl-4-yloxy)-5-pyridin-3-yl-pent-4-yn-3-ol (4.16 g, Example 4c)), 10% palladium on charcoal (0.5 g) in ethyl acetate (100 ml) to give the sub-title compound as a white solid and as a 4:1 mixture of diastereomers (4.13 g).

Provenance & Evidence