HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Chloride → HCID 178418536, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Chloride | HCID 6327 | — |
| Reactant | 4-Chlorophenyl Isocyanate | HCID 7693 | — |
| Reactant | 3-[4-(4-Chlorobenzyl)piperazin-1-yl]propanethiol dihydrochloride | HCID 13731118 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 178418536 | HCID 178418536 | 42.4% |
Reaction Steps
The procedure described in Example 2 was followed, using 1.5 g of 4-chlorophenyl isocyanate, 3.5 g of 3-[4-(4-chlorobenzyl)piperazin-1-yl]propanethiol dihydrochloride, 1.2 g of triethylamine and 50 ml of methyl chloride, to give 1.1 g (21% of theory) of N-(4-chlorophenyl)-S-{3-[4-(4-chlorobenzyl)piperazin-1-yl]propyl}thiocarbamate dihydrochloride monohydrate as an off-white crystalline solid, M.p. 243°-245° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04722926 |
| Source dataset | uspto-grants-1988_02 |
| ORD ID | ord-d33367d8f1b54a0ba584c0599674b958 |
| Source note | uspto-grants-1988_02 |