化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Iodide → 2-(3-Bromophenoxy)acetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Iodide | HCID 4875 | — |
| 反応物 | Chloroacetamide | HCID 6580 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 3-Bromophenol | HCID 11563 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | 2-(3-Bromophenoxy)acetamide | HCID 7818378 | 103.8% |
反応手順
A mixture of 2-chloroacetamide (5.6 g), 3-bromophenol (10 g), potassium carbonate (8.3 g) and potassium iodide (1 g) in acetonitrile was stirred at room temperature for 72 hours. The resulting mixture was filtered, and the solids washed with ethyl acetate, and then water. The dried solids were recrystallised from boiling ethanol: water(8:2) to give the sub-title compound as a solid (13.8 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06300352B1 |
| 出典データセット | uspto-grants-2001_10 |
| ORD ID | ord-763d6c90d8df49af866b04a4a9d681f2 |
| 出典メモ | uspto-grants-2001_10 |