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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 38003Generated: October 26, 2026

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid → (R)-(3-(tert-butyldimethylsilyloxy)pyrrolidin-1-yl)(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanone

https://huagongshe.com/reaction/38003

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acidHCID 2734621—
Reactant(R)-3-(tert-Butyldimethylsilyloxy) pyrrolidineHCID 11830478—
Product(R)-(3-(tert-butyldimethylsilyloxy)pyrrolidin-1-yl)(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanoneHCID 66959643—

Reaction Steps

The title compound was prepared by the procedure as described in Example 101 (Step H) using 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid and (R)-3-(tert-butyldimethylsilyloxy)pyrrolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08524702B2
Source datasetuspto-grants-2013_09
ORD IDord-421b41a70fa54d978afd5162a0be0f19
Source noteuspto-grants-2013_09