HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → HCID 57055044, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | (2S)-2-(4-Bromophenoxy)butanoic acid, methyl ester | HCID 15744155 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 57055044 | HCID 57055044 | 77.5% |
Reaction Steps
Prepared according to the method described in Example 4b) from (2S)-2-(4-bromophenoxy)butanoic acid, methyl ester (7.53 g, Example 87a)) and sodium borohydride (1.09 g) in ethanol (100 ml). After work up, crude material was purified by flash column chromatography over silica eluting with dichloromethane to give the sub-title compound as an oil (5.24 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06300352B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-f6fbe23f31b4410a8a86cbd383bc0315 |
| Source note | uspto-grants-2001_10 |