HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 6-Maleimidohexanoic acid | HCID 573683 | — |
| Product | 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl chloride | HCID 11424716 | — |
Reaction Steps
The 6-maleimidocaproic acid is reacted with excess thionyl chloride at 50° C. for three hours, and then the excess thionyl chloride is distilled off to leave 6-maleimidocaproic chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06300456B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-ef01a791a26a42228eb1b16dad10abed |
| Source note | uspto-grants-2001_10 |