Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | Sodium Persulfate | HCID 62655 | — |
| Reactant | Hexanal, 6-hydroxy- | HCID 190319 | — |
| Solvent | Water | HCID 962 | — |
| Product | 6-Hydroxycaproamide | HCID 11815390 | 40% |
Reaction Steps
5.26 Grams (45 mmols) of 6-hydroxyhexanal was charged to a 100 milliliter Schlenk flask and dissolved in 10 milliliters of deionized water by heating to 85-95° C. in a water bath. The resulting solution was charged to the Parr autoclave containing 0.484 grams of Na2S2O8 and 35 milliliters of NH4OH. The reactor was placed under 400 psi air, heated to 80° C. and a 500 psi air purge was established. The reaction was allowed to proceed for 3 hours. At that time, reaction conversion was virtually complete and 6-hydroxycaproamide was formed in 40% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06300496B1 |
|---|
| Source dataset | uspto-grants-2001_10 |
|---|
| ORD ID | ord-0e35e80626804ba5b793668812997ba6 |
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| Source note | uspto-grants-2001_10 |
|---|
