HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butanol → ClCF2-CH2-O-CF2CFHBr
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butanol | HCID 6386 | — |
| Reactant | 1-Bromo-1,2,2-trifluoroethene | HCID 11730 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 2-Chloro-2,2-difluoroethan-1-ol | HCID 3864148 | — |
| Solvent | Water | HCID 962 | — |
| Product | ClCF2-CH2-O-CF2CFHBr | HCID 21696368 | 89% |
| Product | CF2=CH-O-CF2CFHBr | HCID 88022705 | 11% |
Reaction Steps
In a 50 ml glass reactor equipped with PTFE valve and magnetic stirring, 2.4 g (0.02 moles) of ClCF2—CH2—OH, 5 ml of tert-butyl alcohol, 1.1 g (0.02 moli) of KOH and 3.5 g of CF2═CFBr (0.022 moles) are fed. The reaction mixture is left under stirring at room temperature for three hours. The organic phase is then diluted with water, separated, washed twice with slightly acid water by HCl and anhydrified. 5 g of a mixture having the following composition: 89% ClCF2—CH2—O—CF2CFHBr and 11% CF2═CH—O—CF2CFHBr are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06300526B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-1dc9998e4b1d4138a80acbdb9350282f |
| Source note | uspto-grants-2001_10 |