4-Methylcinnoline → 2-(1-aminopropan-2-yl)aniline

Participants

Reaction Steps

Reduction of 4-methyl-cinnoline (10 g, 69.5 mmol) in methanol (100 mL), using Raney nickel (3 g). The catalyst was removed and washed with methanol. The filtrate was treated with an excess of HCl in isopropanol; ether was then added and the solution cooled. The precipitate was filtered and dried; 9.4 g (60%).

Provenance & Evidence