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HRID38020

反应详情

EQUATION

反应方程式

HRID 38020 的结构方程式

REACTANTS

反应物

4
结构：O[C@H]1CCNC1
HCID2733874

未命名化合物

结构：CC1(C)OB(c2ccc(C(=O)O)cc2)OC1(C)C
HCID2734621

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid

C13H17BO4

结构：CC1(C)OB(c2ccc(C(=O)N3CC[C@H](O)C3)cc2)OC1(C)C
HCID66960471

未命名化合物

结构：CCCN(CCCO[Si](C)(C)C(C)(C)C)C(=O)C1=Cc2ccc(Br)cc2N=C(NC(=O)OC(C)(C)C)C1
HCID86652684

未命名化合物

PRODUCTS

生成物

1
结构：CCCN(CCCO)C(=O)C1=Cc2ccc(-c3ccc(C(=O)N4CC[C@H](O)C4)cc3)cc2N=C(N)C1
HCID51034285

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by the procedure as described in Example 124 (Step F) using tert-butyl (1E,4E)-8-bromo-4-((3-(tert-butyldimethylsilyloxy)propyl)(propyl)carbamoyl)-3H-benzo[b]azepin-2-ylcarbamate and (S)-(3-hydroxypyrrolidin-1-yl)(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanone that was prepared by the procedure as described in Example 101 (Step H) using 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid and (S)-pyrrolidin-3-ol. MS APCI (+) m/z 705 (M+1) detected.

WORKUP

后处理

  1. customwas prepared by the procedure