HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimethylamine → 1,3-Dihydroxy-5-trimethylsiloxyadamantane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimethylamine | HCID 1146 | — |
| Reactant | Chlorotrimethylsilane | HCID 6397 | — |
| Reactant | 1,3,5-Adamantanetriol | HCID 9899022 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1,3-Dihydroxy-5-trimethylsiloxyadamantane | HCID 21930710 | — |
Reaction Steps
This 1,3,5-trihydroxyadamantane was dissolved in methylene chloride. To this solution were added a small amount of trimethylamine, and then an equimolar amount of trimethylsilyl chloride. Reaction was carried out at room temperature. The reaction product was partitioned by high performance liquid chromatography to obtain 1,3-dihydroxy-5-trimethylsiloxyadamantane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06303266B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-c1f12315975a4e23b078209576811615 |
| Source note | uspto-grants-2001_10 |