HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus tribromide → 4-Bromo-3,5-dimethylpyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus tribromide | HCID 24614 | — |
| Reactant | Pyridine, 3,5-dimethyl-4-nitro-, 1-oxide | HCID 96264 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-Bromo-3,5-dimethylpyridine | HCID 22323246 | 31.4% |
Reaction Steps
By proceeding in a similar manner to the procedure contained in J.Chem.Soc., 1956, page 771 but using 4-nitro-3,5-dimethylpyridine-N-oxide (23.06 g), phosphorous tribromide (111.47 g) in toluene (50 ml) there was prepared the title compound (8 g) as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06303600B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-e97c1d476e6c45648fc12a5f2061ab08 |
| Source note | uspto-grants-2001_10 |