HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-methoxyphenol → Methyl 3,5-dinitro-4-(2'-chloro-4'-methoxyphenoxy)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-methoxyphenol | HCID 87459 | — |
| Reactant | Methyl 4-chloro-3,5-dinitrobenzoate | HCID 96161 | — |
| Reactant | Potassium 2-chloro-4-methoxyphenolate | HCID 23716091 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Methyl 3,5-dinitro-4-(2'-chloro-4'-methoxyphenoxy)benzoate | HCID 18349326 | 66% |
Reaction Steps
The dinitro precursor was prepared by reacting 2-chloro-4-methoxyphenol (Aldrich Chemical Co., Milwaukee, Wis.) as the potassium 2-chloro-4-methoxyphenolate with methyl 4-chloro-3,5-dinitrobenzoate, as described in Example 1.2.1. The methyl 3,5-dinitro-4-(2′-chloro-4′-methoxyphenoxy)benzoate product (66% yield) was crystallized from ethanol to give orange crystals. Melting point: 116-119° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06303621B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-9387ae66eb62463d9e5da18a00fd2821 |
| Source note | uspto-grants-2001_10 |