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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 380488Generated: October 30, 2026

4-(3-Phenylpropyl)piperidin-4-ol → 1-Benzyl-3-(RS)-(4-hydroxy-4-(3-phenylpropyl)piperidinylmethyl)-4-(SR)-(3-thienyl)pyrrolidine

https://huagongshe.com/reaction/380488

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3-Phenylpropyl)piperidin-4-olHCID 416903—
Reactant1-Benzyl-3-(SR)-formyl-4-(RS)-(3-thienyl)pyrrolidineHCID 18364719—
Product1-Benzyl-3-(RS)-(4-hydroxy-4-(3-phenylpropyl)piperidinylmethyl)-4-(SR)-(3-thienyl)pyrrolidineHCID 18364900—

Reaction Steps

The title compound was prepared from 1-benzyl-3-(SR)-formyl-4-(SR)-thiophen-3-ylpyrrolidine and 4-hydroxy-4-(3-phenylpropyl)piperidine by procedures described in Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06303593B1
Source datasetuspto-grants-2001_10
ORD IDord-5535296cdf44472985dd8a100f354529
Source noteuspto-grants-2001_10