2,2,2-Trichloroethyl chloroformate → HCID 70214230, compound

Participants

Reaction Steps

A solution of 1.24 g (3.98 mmol) of 1-benzyl-4-(2-(phenylmercapto)-1-ethyl)piperidine and 0.61 mL (4.4 mmol) of 2,2,2-trichloroethylchloroformate in 10 mL of acetonitrile was stirred at rt for 2.5 h. The reaction mixture was concentrated and the residue was purified by chromatography (silica, hexanes:ehtyl acetate, 4:1) to give 1.48 g of the title compound.

Provenance & Evidence