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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 380547Generated: November 2, 2026

HCID 18365238, compound → HCID 17785803, compound

https://huagongshe.com/reaction/380547

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 18365238HCID 18365238—
ReactantHCID 178418361HCID 178418361—
CatalystPlatinum oxide (PtO)HCID 82844—
SolventTetrahydrofuranHCID 8028—
SolventEthyl AcetateHCID 8857—
ProductHCID 17785803HCID 1778580392.2%

Reaction Steps

A mixture of 2.92 gm 1-benzyl-4-(6-methoxynaphth-2-yl)-1,2,3,6-tetrahydropyridine and 0.3 gm platinum oxide in 50 mL tetrahydrofuran and 50 mL ethyl acetate was hydrogenated at room temperature for 16 hours at an initial hydrogen pressure of 60 p.s.i. The reaction mixture was filtered and the filtrate concentrated under reduced pressure to provide 2.71 gm of the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06303627B1
Source datasetuspto-grants-2001_10
ORD IDord-8e9a54cb64af4cd0b54f18b8f63c166d
Source noteuspto-grants-2001_10