HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(1,3-Dioxaindan-5-yl)-2-bromoethan-1-one → Methyl [2-[(1,3-benzodioxol-5-yl)carbonyl]-6-chloro-1H-indol-3-yl]acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(1,3-Dioxaindan-5-yl)-2-bromoethan-1-one | HCID 243777 | — |
| Reactant | methyl [6-chloro-2-[(5,6,7,8-tetrahydroisoquinolin-3-yl)carbonyl]-1H-indol-3-yl]acetate | HCID 9908023 | — |
| Product | Methyl [2-[(1,3-benzodioxol-5-yl)carbonyl]-6-chloro-1H-indol-3-yl]acetate | HCID 9951334 | — |
Reaction Steps
The title compound was prepared according to the procedure described in step 2 of Example 1 from 5-bromoacetyl-1,3-benzodioxole (J.Med. Chem., 1977, 20, 394) and methyl trans-4-chloro-2-[(phenylsulfonyl)amino]cinnamate (Example 1, step 1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06303628B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-ae9addeab3914caabee7f48187873a82 |
| Source note | uspto-grants-2001_10 |