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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 380568Generated: October 27, 2026

5-acetyl-1-ethoxycarbonyl-2,3-dihydro-1H-indole → 5-bromoacetyl-1-ethoxycarbonyl-2,3-dihydro-1H-indole

https://huagongshe.com/reaction/380568

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-acetyl-1-ethoxycarbonyl-2,3-dihydro-1H-indoleHCID 9991583—
Reactant2-Bromo-1-(2,3-dihydro-1H-inden-5-yl)ethan-1-oneHCID 13194125—
Product5-bromoacetyl-1-ethoxycarbonyl-2,3-dihydro-1H-indoleHCID 15453713—

Reaction Steps

*5-bromoacetyl-1-ethoxycarbonyl-2,3-dihydro-1H-indole was prepared from 5-acetyl-1-ethoxycarbonyl-2,3-dihydro-1H-indole (Y. Ishihara et al., J.Chem.. Soc. Perkin Trans.1, 1992, 3401) according to the procedure for preparing 5-bromoacetylindan described in Example 11.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06303628B1
Source datasetuspto-grants-2001_10
ORD IDord-0faa428d2ebc4c4e8e7e0d0b6be7b28e
Source noteuspto-grants-2001_10