Tricyclo(3.3.1.13,7)dec-1-ylmethylamine → HCID 8927630, compound

HRID 380685Notes

Reaction equation

HRID 380685 reaction equation
[C:1]12([CH2:11][NH2:12])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[Br:13][C:14]1[CH:22]=[CH:21][C:20]([F:23])=[CH:19][C:15]=1[C:16](O)=[O:17]>>[Br:13][C:14]1[CH:22]=[CH:21][C:20]([F:23])=[CH:19][C:15]=1[C:16]([NH:12][CH2:11][C:1]12[CH2:8][CH:7]3[CH2:6][CH:5]([CH2:4][CH:3]([CH2:9]3)[CH2:2]1)[CH2:10]2)=[O:17]

Participants

3

Reactant 2

HCID 86625Tricyclo(3.3.1.13,7)dec-1-ylmethylamineHCID 27781812-Bromo-5-fluorobenzoic acid

Product 1

HCID 8927630HCID 8927630, compound

Procedure

Prepared according to the method of Example 41 from 1-adamantanemethylamine (0.1 ml) and 2-bromo-5-fluorobenzoic acid (0.123 g) to give the title compound as a white solid (0.140 g).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-e80d85b03fb446a6bede957215a5ce1a
Source dataset
uspto-grants-2001_10
Patent number
US06303659B2

Reaction notes

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