Dicyclohexylcarbodiimide → HCID 20670034, compound

HRID 380693Notes

Reaction equation

HRID 380693 reaction equation
[Cl:1][C:2]1[C:10]([OH:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.ON1C2C=CC=CC=2N=N1.[C:22]12([CH2:32][NH2:33])[CH2:31][CH:26]3[CH2:27][CH:28]([CH2:30][CH:24]([CH2:25]3)[CH2:23]1)[CH2:29]2.C1(N=C=NC2CCCCC2)CCCCC1>>[Cl:1][C:2]1[C:10]([OH:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH:33][CH2:32][C:22]12[CH2:31][CH:26]3[CH2:25][CH:24]([CH2:30][CH:28]([CH2:27]3)[CH2:29]1)[CH2:23]2)=[O:6]

Participants

5

Reactant 4

HCID 10868DicyclohexylcarbodiimideHCID 757711-HydroxybenzotriazoleHCID 86625Tricyclo(3.3.1.13,7)dec-1-ylmethylamineHCID 156313402-Chloro-3-hydroxybenzoic acid

Product 1

HCID 20670034HCID 20670034, compound

Procedure

Prepared according to the method of Example 38 using 2-chloro-3-hydroxybenzoic acid (0.39 g), 1-hydroxy benzotriazole (0.31 g), 1-adamantanemethylamine (0.4 ml) and 1,3-dicyclo-hexylcarbodiimide (0.47 g) to yield the title compound as a white solid (0.29 g).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-9c87365e8148420b9a555fc72774fee9
Source dataset
uspto-grants-2001_10
Patent number
US06303659B2

Reaction notes

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