HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenyl isocyanate → HCID 178418494, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenyl isocyanate | HCID 7672 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3-[4-(4-Methylbenzyl)piperazin-1-yl]propanethiol dihydrochloride | HCID 13731120 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178418494 | HCID 178418494 | 48.2% |
Reaction Steps
The procedure described in Example 2 was followed, using 1.4 g of phenyl isocyanate, 4.0 g of 3-[4-(4-methylbenzyl)piperazin-1-yl]propanethiol dihydrochloride, 1.2 g of triethylamine and 50 ml of methylene chloride, to give 1.1 g (20% of theory) of N-phenyl-S-{3-[4-(4-methylbenzyl)piperazin-1-yl]propyl}thiocarbamate dihydrochloride sesquihydrate as a white crystalline solid, M.p. 255°-258° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04722926 |
| Source dataset | uspto-grants-1988_02 |
| ORD ID | ord-1a29534138cf42879b452e139d3dd015 |
| Source note | uspto-grants-1988_02 |