反应详情

Using the method of Example 1 step 1: To 5.0 g (23.9 mmole) of 2,3,6-trichloro benzaldehyde in 20 ml acetone, was added 2.3 g 50% aqueous NaOH (28.7 mmole) in 100 ml water; After 4 hours the reaction mixture was worked u to give 5.5 g of the trans-4-(2,3,6-trichlorophenyl)-3-buten-2-one as a yellow oil with solid in a 92.3% yield (99% purity by GLC).