N-(2-(4-Bromophenyl)propyl)propane-2-sulfonamide → HCID 21893383, compound

HRID 380982Notes

Reaction equation

HRID 380982 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([CH:8]([CH3:17])[CH2:9][NH:10][S:11]([CH:14]([CH3:16])[CH3:15])(=[O:13])=[O:12])=[CH:4][CH:3]=1.[CH:18]1([Mg]Cl)[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>>[CH:18]1([C:2]2[CH:7]=[CH:6][C:5]([CH:8]([CH3:17])[CH2:9][NH:10][S:11]([CH:14]([CH3:16])[CH3:15])(=[O:13])=[O:12])=[CH:4][CH:3]=2)[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 9927066N-(2-(4-Bromophenyl)propyl)propane-2-sulfonamideHCID 178478990HCID 178478990, compound

Product 1

HCID 21893383HCID 21893383, compound

Procedure

The title product was prepared from the product of Example 27 as described in Example 15, Condition 2, with the exception that cyclohexylmagnesium chloride was used instead of cyclopentylmagnesium bromide.

Sources & evidence

ORD record
ord-fa3f478a60bb41549ea9fa64fb9c8d9e
Source dataset
uspto-grants-2001_10
Patent number
US06303816B1

Reaction notes

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