1-Propanesulfonyl chloride → HCID 69594915, compound

HRID 381002Notes

Reaction equation

HRID 381002 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:15]=[CH:14][C:13]([CH:16]([CH3:25])[CH2:17][NH:18][S:19]([CH:22]([CH3:24])[CH3:23])(=[O:21])=[O:20])=[CH:12][CH:11]=2)=[CH:6][CH:5]=1.[CH2:26]([S:29](Cl)(=[O:31])=[O:30])[CH2:27][CH3:28]>>[CH2:26]([S:29]([NH:1][CH2:2][CH2:3][C:4]1[CH:5]=[CH:6][C:7]([C:10]2[CH:15]=[CH:14][C:13]([CH:16]([CH3:25])[CH2:17][NH:18][S:19]([CH:22]([CH3:24])[CH3:23])(=[O:21])=[O:20])=[CH:12][CH:11]=2)=[CH:8][CH:9]=1)(=[O:31])=[O:30])[CH2:27][CH3:28]

Participants

3

Reactant 2

HCID 662791-Propanesulfonyl chlorideHCID 21893565HCID 21893565, compound

Product 1

HCID 69594915HCID 69594915, compound

Procedure

The title compound was prepared following the method of Example 147 and using 1 mL of a stock solution of 0.5 g (1.4 mmol) of material from Example 50 and 9.0 μL (0.11 mmol) 1-propanesulfonyl chloride. NMR was consistent with the proposed compound.

Sources & evidence

ORD record
ord-5de63d921f344d3f8c84a4f93c648279
Source dataset
uspto-grants-2001_10
Patent number
US06303816B1

Reaction notes

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