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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 381279Generated: October 30, 2026

4-Bromo-1,2-dichlorobenzene → 2-Chloro-4-(3,4-dichlorophenyl)-6-trifluoromethylpyrimidine

https://huagongshe.com/reaction/381279

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-1,2-dichlorobenzeneHCID 29013—
Reactant2-Chloro-4-(trifluoromethyl)pyrimidineHCID 2773912—
Product2-Chloro-4-(3,4-dichlorophenyl)-6-trifluoromethylpyrimidineHCID 15477740—

Reaction Steps

4A was prepared from 2-chloro-4-trifluoromethyl-pyrimidine and 3,4-dichlorobromobenzene by the method reported for 1A. (Method A) 1H NMR 1H, (8.29,8.28,d) 1H, (8.01,8.00,7.98,7.97,dd) 1H, (7.92,s) 1H, (7.66,7.63,d)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06306866B1
Source datasetuspto-grants-2001_10
ORD IDord-18a4ed0dd33341ffa9278cb61192e20b
Source noteuspto-grants-2001_10