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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 381405Generated: October 31, 2026

1-((2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole, (2R-cis)- → HCID 178462382, compound

https://huagongshe.com/reaction/381405

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-((2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole, (2R-cis)-HCID 10131191—
ReactantHCID 178477146HCID 178477146—
ProductHCID 178462382HCID 17846238231%

Reaction Steps

Reaction and treatment were carried out in the same manner as in Example 1 using (2R,3S)-2-(2,4-difluorophenyl)-3-methyl-2-[(1 H-1,2,4-triazol-1-yl)methyl]oxirane and trans-1-(acetylthio)-4-[(E)-2-(4-chlorophenyl)vinyl]cyclohexane to obtain the desired compound having a melting point of 64 to 66° C. in a yield of 31%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06306880B1
Source datasetuspto-grants-2001_10
ORD IDord-9e91f16e683347f390cd8ebdae73168c
Source noteuspto-grants-2001_10