HCID 10687990, compound → HCID 10827334, compound

HRID 381435Notes

Reaction equation

HRID 381435 reaction equation
[F:1][C:2]([F:23])([CH:20]([F:22])[F:21])[CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8](/[CH:11]=[CH:12]/[CH:13]=[CH:14]/[C:15](OCC)=[O:16])=[CH:7][CH:6]=1.[H-].C([Al+]CC(C)C)C(C)C>>[F:1][C:2]([F:23])([CH:20]([F:21])[F:22])[CH2:3][O:4][C:5]1[CH:6]=[CH:7][C:8](/[CH:11]=[CH:12]/[CH:13]=[CH:14]/[CH2:15][OH:16])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 10687990HCID 10687990, compoundHCID 21225700Diisobutylaluminumhydride

Product 1

HCID 10827334HCID 10827334, compoundYield 95%

Procedure

Ethyl (2E,4E)-5-[4-(2,2,3,3-tetrafluoropropoxy)phenyl]-2,4-pentadienoate was treated with diisobutyl aluminum hydride in the same manner as in Reference example 21 to obtain the title compound having a melting point of 95 to 97° C. in a yield of 95%.

Sources & evidence

ORD record
ord-a30f9688df524289a07f69f11394c4d7
Source dataset
uspto-grants-2001_10
Patent number
US06306880B1

Reaction notes

Loading…