HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride → N-(2-methyl-4-nitrophenyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | 2-Methyl-4-nitroaniline | HCID 7441 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | N-(2-methyl-4-nitrophenyl)benzamide | HCID 2835288 | 95% |
Reaction Steps
To a suspension of 2-methyl-4-nitroaniline (0.76 g, 5 mmol) in toluene (25 mL) was added neat benzoyl chloride (0.59 mL, 5.08 mmol). The reaction mixture was refluxed for 16 hr, cooled and filtered to give N-(2-methyl-4-nitrophenyl)benzamide (1.21 g, 95%) as a beige solid. ES-MS (M+H)+=257.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08524721B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-cfb21d133e044f9098f617d99185e3d2 |
| Source note | uspto-grants-2013_09 |