HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tryptamine → 1-(4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tryptamine | HCID 1150 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 4-Methoxybenzaldehyde | HCID 31244 | — |
| Product | 1-(4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole | HCID 198916 | 80% |
Reaction Steps
This product was prepared using the same procedure as for Intermediate 1 with tryptamine (15 g, 94.9 mmol), 4-methoxybenzaldehyde (12.9 g, 1.1 equiv.) and TFA (14.6 mL, 2 equiv.) to give the title compound (20.9 g, 80%) as a brownish powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06306870B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-cbdb93b86752458e8491b5350bd19dbb |
| Source note | uspto-grants-2001_10 |