Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 381468Generated: October 31, 2026

Tryptamine → HCID 18363100, compound

https://huagongshe.com/reaction/381468

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTryptamineHCID 1150—
ReactantTrifluoroacetic acidHCID 6422—
Reactantp-(Trifluoromethoxy)benzaldehydeHCID 69573—
ProductHCID 18363100HCID 1836310038.5%

Reaction Steps

This product was prepared using the same procedure as for Intermediate 1 with tryptamine (2.0 g, 12.5 mmol), 4-trifluoromethoxybenzaidehyde (2.4 g, 1 equiv.) and TFA (1.9 mL, 2 equiv.) to give the title compound (1.6 g, 38%) as a white powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06306870B1
Source datasetuspto-grants-2001_10
ORD IDord-d298514e1d9f46ed884143e1a9a37eef
Source noteuspto-grants-2001_10