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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 381529Generated: October 31, 2026

Hydrochloric Acid → HCID 54153740, compound

https://huagongshe.com/reaction/381529

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 54051298HCID 54051298—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 54153740HCID 54153740—

Reaction Steps

A solution of 2-[5-(2-Methoxycarbonyl-ethyl)-thiazol-2-yl]-pyrrolidine-1-carboxylic acid tert-butyl ester (0.37 g, 1.09 mmol) in a solution of hydrochloric acid in dioxane (4N, 10 mL) was stirred at room temperature for 1 h. The solvent was removed in vacuo and the residue dissolved in methylene chloride. The methylene chloride was removed in vacuo and the residue dissolved again in methylene chloride. The solvent was removed in vacuo and the residue used without purification. MS: Calc'd for C11H16N2O2S: 240.09. Found (M+1): 241.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06306887B1
Source datasetuspto-grants-2001_10
ORD IDord-50ad3e0d65f64bb5b55291c7eb572cee
Source noteuspto-grants-2001_10