Butylamine → Melamine, butyl- (8CI)

HRID 381654Notes

Reaction equation

HRID 381654 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[N:5]=[C:4](Cl)[N:3]=1.[CH2:10]([NH2:14])[CH2:11][CH2:12][CH3:13]>O>[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[N:5]=[C:4]([NH:14][CH2:10][CH2:11][CH2:12][CH3:13])[N:3]=1

Participants

4

Reactant 2

HCID 8007ButylamineHCID 188311,3,5-Triazine-2,4-diamine, 6-chloro-

Product 1

HCID 197831Melamine, butyl- (8CI)Yield 96%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixed solution of 14.5 g (0.1 mol) of 2,4-diamino-6-chloro-1,3.5-triazine synthesized in Reference Example 1, 100 ml of water and 29.2 g (0.4 mol) of butylamine was warmed with stirring to the reflux temperature finally at which the reaction was allowed to proceed for 6 hours. After cooling the reaction mixture, the product was filtered off and further sufficiently washed with a large amount of water and then with toluene. the filtrate was dried at 70° C. for 6 hours under vacuum to obtain 17.5 g (yield: 96%) of the titled compound. Melting point: 167° C.

Workup

  1. temperaturewas warmed
  2. temperatureAfter cooling the reaction mixture
  3. filtrationthe product was filtered off
  4. washfurther sufficiently washed with a large amount of water
  5. customthe filtrate was dried at 70° C. for 6 hours under vacuum

Sources & evidence

ORD record
ord-42818e080398473db2049488ac9a66f0
Source dataset
uspto-grants-2001_10
Patent number
US06307046B1

Reaction notes

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