2-Ethylhexanol → HCID 57483901, compound

HRID 381696Notes

Reaction equation

[CH2:1]([CH:3]([CH2:6][CH2:7][CH2:8][CH3:9])[CH2:4][OH:5])[CH3:2].[C:10]([N:13]1[C:17](=[O:18])[CH:16]=[CH:15][C:14]1=[O:19])(=[O:12])[NH2:11]>>[C:17]([O:5][CH2:4][CH:3]([CH2:1][CH3:2])[CH2:6][CH2:7][CH2:8][CH3:9])(=[O:18])/[CH:16]=[CH:15]\[C:14](=[O:19])[NH:13][C:10](=[O:12])[NH2:11]

Participants

Reactant 2

HCID 77202-Ethylhexanol

HCID 76868N-Carbamylmaleimide

Product 1

HCID 57483901HCID 57483901, compoundYield 95%

Procedure

The addition of 2-ethylhexanol to N-carbamylmaleimide under the conditions of Example C afforded a 95% yield of 2-ethylhexyl maleurate. M.P.: 73°-6° C.; 1H NMR (CDCl3): δ10.6 (br s, 1H), 8.2 (br s, 1H), 6.3 (m, 2H), 5.8 (br s, 1H), 4.2 (m, 2H), 1.6 (m, 1H), 1.3 (m, 8H), 0.9 (t, 6H); HPLC (40% CH3CN/H2O, C8): Rt=14.2 minutes.

Sources & evidence

ORD record: ord-1810b883c02e425693ad127b2e15a4b3
Source dataset: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06307058B1

Reaction notes

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