HRID381711

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@H]21.[O-]B[O-]

HCID178445512

未命名化合物

2 次

HCID178514824

未命名化合物

PRODUCTS

生成物

结构：CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@H]21

HCID54454

Simvastatin

C25H38O5

PROCEDURE

实验过程

Alternatively, III may be dissolved in an organic solvent and recirculated over a supported diol or polyol stationary phase to which the boronate moiety of III becomes attached. The organic solution is concentrated to obtain simvastatin.

WORKUP

后处理

concentrationThe organic solution is concentrated