Glycerol → 2,2-Dihexyl-4-hydroxymethyl-1,3-dioxolane

HRID 381722노트

반응식

HRID 381722 반응식
[CH3:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7](=[O:14])[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].[OH:15][CH2:16][CH:17]([CH2:19]O)[OH:18]>C1(C)C=CC(S(O)(=O)=O)=CC=1.C1(C)C=CC=CC=1>[CH2:8]([C:7]1([CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][CH3:1])[O:18][CH:17]([CH2:16][OH:15])[CH2:19][O:14]1)[CH2:9][CH2:10][CH2:11][CH2:12][CH3:13]

참가 물질

5

반응물 2

HCID 753GlycerolHCID 100157-Tridecanone

생성물 1

HCID 183640342,2-Dihexyl-4-hydroxymethyl-1,3-dioxolane

시약·촉매·용매 2

HCID 6101p-Toluenesulfonic acid촉매HCID 1140Toluene용매

실험 절차

A reactor equipped with a stirrer, reflux-condenser, thermometer and nitrogen gas inlet pipe was charged with 297 g of 7-tridecanone, 166 g of glycerol and a solvent amount of toluene, and after addition of p-toluenesulfonic acid as a catalyst, the dehydrative condensation reaction was carried out at the reflux temperature for 24 hours. The resulting crude product was washed with an aqueous solution of potassium carbonate and further with 3 portions of distilled water and finally purified by distillation under reduced pressure to provide 2,2-dihexyl-4-hydroxymethyl-1,3-dioxolane.

후처리

  1. customA reactor equipped with a stirrer, reflux-condenser
  2. customthe dehydrative condensation reaction
  3. washThe resulting crude product was washed with an aqueous solution of potassium carbonate and further with 3 portions of distilled water
  4. distillationfinally purified by distillation under reduced pressure

출처 및 근거

ORD 기록
ord-a5883a5f50bb4fdba99164c150315bd3
출처 데이터셋
uspto-grants-2001_10
특허 번호
US06307069B1

반응 노트

불러오는 중…