2-Amino-2-phenylethanol → HCID 53653707, compound

HRID 381737Notes

Reaction equation

HRID 381737 reaction equation
[C:1]1([CH:7]([CH2:9][OH:10])[NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[CH2:12]/[CH:13]=[CH:14]\[CH2:15]Cl>>[C:1]1([C@@H:7]([N:8]2[CH2:15][CH:14]=[CH:13][CH2:12]2)[CH2:9][OH:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 924662-Amino-2-phenylethanolHCID 64321151,4-Dichloro-cis-2-butene

Product 1

HCID 53653707HCID 53653707, compoundYield 58%

Procedure

This was prepared from R-(−)-(2-phenylglycinol and cis-1,4-dichloro-2-butene in 58% yield according to the procedures similar to those described in Preparation 1.

Workup

  1. customthose described in Preparation 1

Sources & evidence

ORD record
ord-44ae17167c3d440c8157a0c90fd11f7e
Source dataset
uspto-grants-2001_10
Patent number
US06307061B2

Reaction notes

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