Methyl 4-methylaminobenzoate → HCID 20640609, compound

HRID 381747Notes

Reaction equation

HRID 381747 reaction equation
[F:1][C@H:2]1[CH2:6][CH2:5][N:4]([CH2:7][C@H:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)O)[CH2:3]1.F[C@H]1CCN([C@H](C2C=CC=CC=2)CO)C1.[CH3:31][NH:32][C:33]1[CH:42]=[CH:41][C:36]([C:37]([O:39][CH3:40])=[O:38])=[CH:35][CH:34]=1>>[F:1][C@H:2]1[CH2:6][CH2:5][N:4]([CH2:7][C@@H:8]([N:32]([C:33]2[CH:42]=[CH:41][C:36]([C:37]([O:39][CH3:40])=[O:38])=[CH:35][CH:34]=2)[CH3:31])[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH2:3]1

Participants

4

Reactant 3

HCID 140375Methyl 4-methylaminobenzoateHCID 20640576HCID 20640576, compoundHCID 20640577HCID 20640577, compound

Product 1

HCID 20640609HCID 20640609, compoundYield 54%

Procedure

This was prepared from 2-(3-(S)-fluoropyrrolidin-1-yl)-1-(S)-phenylethanol and 2-(3-(S)-fluoropyrrolidin-1-yl)-2-(R)-phenylethanol and methyl 4-methylaminobenzoate in 54% yield according to a procedure similar to that described in Example 1 (i).

Sources & evidence

ORD record
ord-b5f41ddec80c4fde81ecf45527a13fd5
Source dataset
uspto-grants-2001_10
Patent number
US06307061B2

Reaction notes

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