1H-indazol-3-amine → [2-(2-Chloro-phenyl)-pyrido[3,4-d]pyrimidin-4-yl]-(1H-indazol-3-yl)-amine

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1H-indazol-3-amine	HCID 13399	—
Edukt	4-Chloro-2-(2-chloro-phenyl)-pyrido[3,4-d]pyrimidine	HCID 21939210	—
Produkt	[2-(2-Chloro-phenyl)-pyrido[3,4-d]pyrimidin-4-yl]-(1H-indazol-3-yl)-amine	HCID 21939198	—

Reaktionsschritte

Prepared from 4-Chloro-2-(2-chloro-phenyl)-pyrido[3,4-d]pyrimidine (100 mg, 0.36 mmol) and 1H-indazol-3-ylamine (88 mg, 0.66 mmol). Purification by preparative HPLC afforded the title compound as a yellow, di-TFA salt (72 mg, 33% yield).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08524720B2
Quelldatensatz	uspto-grants-2013_09
ORD ID	ord-d81507c348be4c24ad51502661501c88
Quellennotiz	uspto-grants-2013_09