Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 4-(4'-Tert-butyl-biphenyl-4-yl)-4-oxo-butyric acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 4-(4'-Tert-butyl-biphenyl-4-yl)-4-oxo-butyric acid, methyl ester | HCID 70212258 | — |
| 용매 | MeOH tetrahydrofuran | HCID 21899815 | — |
| 생성물 | 4-(4'-Tert-butyl-biphenyl-4-yl)-4-oxo-butyric acid | HCID 18364135 | 76.3% |
반응 단계
In a manner similar to Example 17, Step (b), 4-(4′-tert-butyl-biphenyl-4-yl)-4-oxo-butyric acid, methyl ester (0.43 g, 0.0013 mol) was allowed to react with 1.0 M aqueous sodium hydroxide (2.0 mL, 0.002 mol) in THF-methanol (5 mL each) to give 0.308 g of 4-(4′-tert-butyl-biphenyl-4-yl)-4-oxo-butyric acid as a white solid; mp 172.0-173.5° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06307089B2 |
| 출처 데이터셋 | uspto-grants-2001_10 |
| ORD ID | ord-0c9a00ffe5884376ab8ea7eba4bdac40 |
| 출처 메모 | uspto-grants-2001_10 |