3-Biphenyl-4-yl-2,5-dihydro-2,5-dimethoxyfuran → 3-Biphenyl-4-yl-2,5-dimethoxytetrahydrofuran

Participants

Reaction Steps

A mixture of 3-biphenyl-4-yl-2,5-dihydro-2,5-dimethoxyfuran (1.00 g, 3.55 mmol) and 5% Pd/C (300 mg) in EtOH:EtOAc (1:2) was stirred under H2 atmosphere for 1.75 hours. The catalyst was filtered onto Celite. The filtrate was concentrated to provide 0.97 g (97%) of a diastereomeric mixture of 3-biphenyl4-yl-2,5-dimethoxy-tetrahydro-furan as a colorless oil which was typically used without purification.

Provenance & Evidence