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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 382147Generated: October 29, 2026

HCID 70097645, compound → 3(R)-[3-(4-cyanophenyl)-1H-pyrrol-1-yl]-N-[2,2-dimethyl-1(S)-(methylcarbamoyl)propyl]succinamic acid

https://huagongshe.com/reaction/382147

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 70097645HCID 70097645—
SolventMethanolHCID 887—
SolventEthyl AcetateHCID 8857—
Product3(R)-[3-(4-cyanophenyl)-1H-pyrrol-1-yl]-N-[2,2-dimethyl-1(S)-(methylcarbamoyl)propyl]succinamic acidHCID 1548794790%

Reaction Steps

According to the procedure described in Example 1(a), 3(R)-[3-(4-cyanophenyl)-1H-pyrrol-1-yl]-N-[2,2-dimethyl-1(S)-(methylcarbamoyl)propyl]succinamic acid benzyl ester in MeOH and EtOAc was hydrogenolyzed to provide 1.2 g (90%) of 3(R)-[3-(4-cyanophenyl)-1H-pyrrol-1-yl]-N-[2,2-dimethyl-1(S)-(methylcarbamoyl)propyl]succinamic acid as a yellow powder, mp 138-40° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06306892B1
Source datasetuspto-grants-2001_10
ORD IDord-4b6b7a79624a43938c2f8b09fae73cb1
Source noteuspto-grants-2001_10