HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzonitrile, 4-bromo- → 4-(Furan-3-yl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzonitrile, 4-bromo- | HCID 12162 | — |
| Reactant | Furan-3-boronic acid | HCID 2734358 | — |
| Reactant | 4-(Furan-3-yl)pyridine | HCID 10855602 | — |
| Product | 4-(Furan-3-yl)benzonitrile | HCID 11622400 | — |
Reaction Steps
As described in Example 1(d) for the preparation of 3-(pyridin-4-yl)furan, 4-bromobenzonitrile (4.00 g, 22.0 mmol) was coupled to 3-furanboronic acid to furnish in high yield crude 3-(4-cyanophenyl)-furan as a brown solid, mp 55-7° C., which was used immediately without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06306892B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-47c73f0239474a3fad6e946d9cc45d2e |
| Source note | uspto-grants-2001_10 |