Propanal → HCID 15907301, compound

Participants

Reaction Steps

The 2,4-dimethyl-5-phenylpentan-1-yl derivatives in accordance with the present invention can be prepared by a variety of ways. For example, by an Aldol condensation between 2-methyl-3-phenylpropanal and proprionaldehyde, followed by hydrogenation of the resulting α,β-unsaturated aldehyde to form the saturated aldehyde, 2,4-dimethyl-5-phenylpentanal as described above. This aldehyde is the direct precursor for the alcohol, 2,4-dimethyl-5 -phenylpentan-1-ol via reduction with, e.g. sodium borohydride, as well as the nitrile, 2,4-dimethyl-5-phenyl-pentanitrile via oxidation dehydration chemistry by reaction of hydroxylamine/formic acid as described above.

Provenance & Evidence